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These lists could be connected to external World wide web expert services or immediately accustomed to deliver gene signatures for the from signature to drug module of GDA. (B) The output web page in the drug clustering returns an interactive clustering tree of all significant medications grouped by structural similarity.
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(B) Results might be visualized regarding (from top left to bottom suitable): rating and P-price of statistically important compounds; distribution of compound scores grouped by drug family members; distribution of relative sensitivity in mutant/responsive and wild-sort/non-responsive cell lines; gene expression degree of the selected gene in mutant/responsive and wild-kind/non-responsive mobile traces.
modules, genes and compound are chosen via a drop-down menu that automobile-completes dependant on the gene mutations and medicines present inside the databases. From the from signature to drug
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